I've been a long time fan of bison as a beef replacement. See:
Stupid Cows
Now foodies on the Cosasts are taking it up as the latest food trend according to the NYT:
Plains Giants Have Foothold on Tables
What happened, producers and retailers say, is that the buffalo, the great ruminant of the Plains — once endangered, now raised on ranches by the tens of thousands — has thundered into an era of growing buyer concern about where food comes from, what an animal dined on and how it all affects the planet.
Trendsetting consumers and restaurants on the East and West Coasts caught on. Grass-fed, sustainable and locally grown, obscure concepts to most people 15 years ago or so when the buffalo meat market first emerged, became buzzwords of the foodie culture.